Just at the end.
For instance: add these numbers together: 0.545, 0.545, 0.545, 0.545, 0.545:
Unrounded, you get 2.725.
If you round at the end (to the nearest hundredth), you'll get 2.73.
If you round at every step, you would have 0.55, 0.55, 0.55, 0.55, 0.55 for a total of 2.75, which is too large.
Sometimes, it will make no difference; but, to be save, only round the last answer.